Brain Enhance
Gadolinium-free contrast-enhanced MRI powered by deep learning. Our AI synthesises contrast-enhanced brain images from standard FLAIR, T1 and T2 sequences — eliminating the need for gadolinium injection while preserving diagnostic quality.
Why Brain Enhance?
Traditional contrast-enhanced MRI requires intravenous gadolinium — a heavy-metal agent linked to side-effects and contraindicated for many patients. Brain Enhance removes that barrier entirely.
Patient Safety First
Eliminates gadolinium exposure, removing risks of nephrogenic systemic fibrosis (NSF), allergic reactions, and heavy-metal deposition in the brain.
Faster Workflow
No IV line, no contrast injection wait-time, no post-injection monitoring. Reduce scan-to-report turnaround and increase patient throughput.
Broader Access
Enables contrast-equivalent imaging for patients with kidney disease, allergies, or pregnancy who would otherwise be unable to receive gadolinium.
Cost Reduction
Cuts contrast agent procurement costs, shortens scan sessions, and reduces nursing overhead associated with IV administration.
Diagnostic Confidence
Generates high-fidelity synthetic contrast with validated structural similarity, empowering radiologists with reliable tumour visibility.
Seamless Integration
Works with existing MRI hardware and PACS infrastructure. Feed standard FLAIR, T1 and T2 sequences and receive enhanced output instantly.
How It Works
Brain Enhance uses a 3D convolutional neural network with attention mechanisms to learn the mapping between non-contrast sequences and contrast-enhanced MRI.
Acquire Sequences
Standard FLAIR, T1 and T2 MRI volumes are captured using existing scanners.
Normalise & Align
Contrast normalisation and spatial alignment prepare the 3D volume for the network.
Neural Network Prediction
A 3D U-Net with attention analyses multi-sequence features to predict contrast enhancement patterns.
Tumour Enhancement
A dedicated contrast-enhancement block highlights tumour regions with precision.
Enhanced Output
A sharpened, contrast-enhanced volume ready for radiologist review — no gadolinium required.
Clinical Applications
Brain Enhance supports radiologists across a range of critical diagnostic scenarios.
Tumour Detection & Monitoring
Visualise enhancing lesions and track tumour progression over time without repeated gadolinium exposure, especially important for longitudinal follow-up.
Renal-Impaired Patients
Provide contrast-equivalent imaging for patients with chronic kidney disease or renal failure, who are otherwise excluded from gadolinium-based studies.
Paediatric & Pregnancy Imaging
Offer a safer contrast alternative for vulnerable patient populations where minimising chemical exposure is a clinical priority.